What happens when you mix CBD and caffeine?

What happens when you mix CBD and caffeine?

Caffeine is as normal of a presence in our lives as the sun in the sky. Businesses make billions selling drinks filled with it, and people across income brackets admit they can't live their lives without it. With how standard it is, it's weird to think of caffeine as a drug. It is a drug, though, don't be mistaken.

To a similar extent, CBD is in the same position in our society. With the amount of people who take it nowadays, it's become odd to think of it as a drug too. Like other drugs, though, CBD and caffeine can affect our bodies in all sorts of ways. In turn, they can interact with each other and change the effects in ways we can't predict.

For that reason, we need to take a closer look at both CBD and caffeine. Then, from there, we can consider what happens when they enter our system together.


Even those familiar with CBD can get confused about how it works. It, like other cannabinoids, interacts with the endocannabinoid system in the body. This system helps the brain manage the sleep cycle, pain, pleasure, mood, body temperature, and more.

The way CBD interacts with the system, though, is distinct from THC and other cannabinoids. While THC binds directly with cannabinoid receptors, CBD stimulates the system in an indirect manner to release beneficial endocannabinoids. It's the effect of these compounds that we associate with the experience of taking CBD.


Most of you know how caffeine makes you feel. That being said, it's not common for people to know how it actually works.

It all starts in the bloodstream, where caffeine is absorbed within 45 minutes of ingestion. During that process, caffeine begins to interact with the brain under a false impression. See, to the brain, caffeine looks just like adenosine, which is a chemical in all human cells that promotes sleep and slowed nerve activity.

So, even though its effects are almost the opposite, caffeine binds with adenosine receptors due to a similar structure. Since all the receptors are taken up, cells can't sense adenosine anymore, and their activity speeds up. The brain's vessels then constrict, and excitatory neurotransmitters start to increase in the brain. In that moment, you're feeling the full effects of caffeine, which can last up to 4–6 hours.


Now that we know how both CBD and caffeine work, we can consider how they interact. Since they target different receptors in the brain, they don't interact directly in that sense. However, there's a glaring lack of research into the combination of these two drugs. There is one recent study showing how caffeine can potentially prevent memory loss caused by high CBD doses. This study, however, was performed on zebrafish, so more tests need to be done. Both drugs, though (more so CBD), have a strong safety profile, and there are no reported instances of anyone suffering a health issue from the combo.


If you've decided you're ready to try the combo, you should know the best possible approaches to doing so. Dispensaries and health shops sell products combining the two, but there are ways you can combine them yourself if you want.


Considering everyone's turning anything into edibles these days, you shouldn't be surprised that CBD coffee exists. What might surprise you, though, is that it's become so popular that famous stoner Willie Nelson made his own brand. He's got competition, too, especially with brands like Flower Power Coffee Co. almost solely dedicated to the infused beans.

These, though, are pre-infused, so the CBD:caffeine ratio is out of your control. One drinker noted being able to control the dose by having some regular coffee first, but that's just one person. All of our brains work differently, and we might need higher or lower doses of certain substances than other people. If you want to figure out your optimal dose, you should consider infusing CBD into your own coffee.

Your best approach here is to add CBD-infused butter directly into your brewed coffee. We have a recipe for doing this with THC, and the same instructions apply if you're using CBD-heavy strains. If you don't have flower available, you could just add CBD oil directly into regular butter, or even drop the oil right in your coffee. If you take that route, though, you need to keep in mind that the oil is far more concentrated than flower. Furthermore, pouring it in the butter or coffee means it won't affect you as strongly as if you dropped it under your tongue.


Want a more clear-cut way to measure your doses? Taking CBD capsules with your coffee could be the solution there. Since, of course, every capsule has the same amount of CBD inside, you'll know your exact ratio of CBD:coffee. You won't know exactly how much caffeine is in your coffee, but if you're drinking the same coffee daily, that shouldn't be an issue. It's not as convenient as CBD-infused coffee, but you won't have to experiment with dosing nearly as often.

Now, if you're wondering where to get the capsules, we have some good news. Just head over to our online shop, and you'll find some of the best CBD capsules on the market. You can also find a solid selection of oils, supplements, and even topical products.